{ "von willebrand factor":{ "type":[ "noun" ], "definitions":{ ": a large glycoprotein clotting factor circulating in blood plasma that mediates platelet adhesion to collagen at sites of vascular injury, that binds to and protects factor VIII from degradation, and that is deficient or defective in individuals affected with von Willebrand disease":[] }, "pronounciation":[ "v\u00e4n-\u02c8vil-\u0259-\u02ccbr\u00e4nt-" ], "synonyms":[], "antonyms":[], "synonym_discussion":"", "examples":[], "history_and_etymology":{ "after Erik Adolf von Willebrand \u20201949 Finnish physician":"" }, "first_known_use":{ "1970, in the meaning defined above":"" }, "time_of_retrieval":"20220709-090251" }, "von Willebrand disease":{ "type":[ "noun" ], "definitions":{ ": a genetic blood disorder marked by prolonged, excessive, or abnormal bleeding that commonly results in recurrent nosebleeds, heavy menstrual flow, and bleeding from the gums, is caused by deficient or defective von Willebrand factor , and typically occurs in a mild form that is less serious than hemophilia":[] }, "pronounciation":[ "-\u02ccbr\u00e4nt-", "v\u00e4n-\u02c8vi-l\u0259-\u02ccbr\u00e4nt-" ], "synonyms":[], "antonyms":[], "synonym_discussion":"", "examples":[], "history_and_etymology":{ "after Erik Adolf von Willebrand \u20201949 Finnish physician":"" }, "first_known_use":{ "1941, in the meaning defined above":"" }, "time_of_retrieval":"20220709-100744" }, "von Willebrand factor":{ "type":[ "noun" ], "definitions":{ ": a large glycoprotein clotting factor circulating in blood plasma that mediates platelet adhesion to collagen at sites of vascular injury, that binds to and protects factor VIII from degradation, and that is deficient or defective in individuals affected with von Willebrand disease":[] }, "pronounciation":[ "v\u00e4n-\u02c8vil-\u0259-\u02ccbr\u00e4nt-" ], "synonyms":[], "antonyms":[], "synonym_discussion":"", "examples":[], "history_and_etymology":{ "after Erik Adolf von Willebrand \u20201949 Finnish physician":"" }, "first_known_use":{ "1970, in the meaning defined above":"" }, "time_of_retrieval":"20220709-215321" } }